A new technology with very small devices made from genetic material traps viral cells before they can infect human cells.
According to News i and quoting IyaResearchers at the Technical University of Munich (TUM) have developed a new treatment that traps viral infections and makes viruses safer.
Using DNA origami, researchers have developed nanocapsules made from genetic material that can be neutralized by embracing viruses.
The “world origami” method basically programs a world to fold and fold into three-dimensional, triangular plates.
The team that invented this new technology has been working and experimenting on world programming for years. For their latest work, they have created “hollow nanoparticles” that basically trap viruses and prevent them from infecting other cells.
These small traps consist of 20 triangular surfaces, and the inside of the traps is covered with molecules that attach to viruses.
“Even a simple shell of the right size shows a significant reduction in virus activity,” said Hendrik Dietz, author of the article. If we put five binding sites for the virus inside these traps, for example the right antibodies, we can neutralize the virus by up to 80%, and if we consider more, we will achieve complete blocking and neutralization.
Researchers say these viral traps can be used for targeted therapies.
The team tested their traps on cultured mice, human cells and viruses, and found that these small structures remained stable for 24 hours, trapping two types of hepatitis B virus and adeno-associated virus (AAV). And prevented them from infecting human cells.
Dietz also explained that the technology could be used as a means of transporting drugs through the body.
German researchers plan to test their viral traps inside mice. They believe that their “digital origami” structures will eventually be injected into humans, allowing special therapies that trap the virus cells before infecting them.